Rejuran

Rejuran contains Polynucleotide Rejuran (PDRN), derived from salmon DNA, which promotes hydration, regeneration, and overall skin health.
Rejuran is primarily composed of polynucleotides (PN), which are DNA fragments derived from salmon. These polynucleotides are biocompatible and safe, having been purified and processed to be used medically. Salmon DNA is chosen because its nucleotide sequence is remarkably similar to human DNA, which enhances its compatibility and effectiveness in human skin treatments.

Polynucleotides are chains of nucleotides, which are essentially the building blocks that make up DNA. DNA controls many important bodily functions, including how the skin develops. When polynucleotide chains are introduced to the skin (through multiple small injections), they help damaged DNA cells in the skin to repair and as a result, the cells function better. For instance, polynucleotides stimulate fibroblast cells, which help form connective tissues like collagen and elastin – the essential proteins that provide the skin with shape, volume, and a youthful appearance. 

The polynucleotide chains can also:

• improve the extracellular matrix of skin cells, boosting hydration

• stabilise pigmentation

• reduce inflammation.

Polynucleotide treatments can also have an anti-free radical action, helping to counteract and protect the skin from factors like stress and the sun.  

In this sense, polynucleotides are a type of ‘regenerative’ treatment, meaning they change how DNA is expressed, encouraging the body’s natural mechanisms to generate healthier skin cells. 

 Polynucleotides work at a deeper level to repair the DNA of the skin cells and encourage the natural production of elastin and collagen

By encouraging cell growth and turnover, improving elasticity, hydrating the skin, and offering anti-inflammatory properties, polynucleotides can help treat a range of concerns, such as: 

• wrinkles, lines and sunken skin as a result of lost collagen and elastin in the ageing process

• dry, dehydrated skin

• dark circles

• rosacea 

• acne scarring

• hyperpigmentation.

Cell turnover is the natural, continuous process where your body sheds dead skin cells from the surface and replaces them with new, fresh cells from deeper layers, crucial for maintaining healthy, smooth, and radiant skin. This cycle slows with age, leading to dullness, rough texture, and signs of aging, making it a key focus in skincare to encourage faster renewal. 

Rejuran triggers a series of fundamental changes within the skin due to its unique composition:

• Collagen Synthesis: By simulating the body’s natural skin repair processes, Rejuran promotes the synthesis of collagen, essential for maintaining skin elasticity and reducing the appearance of fine lines and wrinkles.

• Skin Barrier Enhancement: It helps strengthen the skin’s barrier, improving its resilience against environmental pollutants and reducing moisture loss.

• Tissue Regeneration: Rejuran aids in the regeneration of damaged skin tissues, making it particularly effective in healing scars and other skin imperfections.

Cellular Repair: The treatment accelerates the natural cellular repair processes, leading to healthier and more vibrant skin over time.

Full Face
Rejuran is particularly effective in treating the facial area, where signs of ageing are most visible. It is commonly used to improve skin texture, reduce fine lines and wrinkles, and enhance overall skin radiance. Areas within the face that can benefit from Rejuran include the forehead, cheeks, around the eyes, and around the mouth.

Eye Area
Rejuran is particularly effective around the eye area, where it reduces dark circles and improves skin firmness, diminishing fine lines and crow’s feet. This makes it a valuable treatment for rejuvenating this delicate facial region.

Rejuran can also be used on other parts of the body that require skin rejuvenation. This includes areas like the neck, hands, arms, legs, and abdominal area, particularly useful for improving skin texture and appearance after weight loss or pregnancy.

Who is Rejuran® Best For?
Rejuran® Eye is ideal for individuals looking to restore and rejuvenate the delicate under-eye area. It is particularly beneficial for those who experience:

• Dark Circles – Helps brighten pigmentation and improve circulation for a refreshed look

• Fine Lines & Wrinkles – Smooths and firms aging, crepey skin under the eyes

• Loss of Elasticity & Firmness – Boosts collagen production to strengthen and tighten the skin

• Puffiness & Eye Bags – Reduces inflammation and enhances skin regeneration

• Tired, Dull Eyes – Revitalizes and deeply hydrates for a more youthful, radiant appearance

• Sun-Damaged or Fragile Skin – Repairs damage from UV exposure and environmental stressors

This treatment is perfect for those looking for a natural, non-surgical solution to refresh and restore their under-eye area with long-lasting, regenerative results.

Pre and post care
What can I expect after my treatment?
Rejuran® Eye is a minimally invasive treatment with mild and temporary side effects. These may include:

• Redness – Common immediately after treatment, usually subsiding within 24-48 hours.

• Swelling – Mild puffiness may occur but typically resolves within a few days.

• Bruising at Injection Sites – Some individuals may experience minor bruising, which fades naturally over time.

 

These symptoms vary based on individual skin sensitivity and typically subside within a few days. Following post-care instructions will help minimise any discomfort and support optimal healing.
Rejuran® Eye works by stimulating collagen production and skin regeneration, so results appear gradually:
1-2 Weeks: Initial improvements in hydration and skin texture as inflammation subsides.
4-6 Weeks: Noticeable reduction in fine lines, wrinkles, and dark circles as collagen production increases.
For optimal, long-lasting results, a series of 3-4 treatments spaced 3-4 weeks apart is recommended.
 

How does the Rejuran work?
Rejuran® Eye is an advanced bio-regenerative injectable treatment designed to repair and rejuvenate the delicate under-eye skin. It uses polynucleotides (PN) derived from Wild Salmon DNA, which stimulate natural skin regeneration, improve elasticity, and enhance hydration.

The Science Behind Rejuran® Eye

• Polynucleotides (PN): These naturally derived molecules support deep skin repair and regeneration.

• Collagen Stimulation: Encourages natural collagen production to improve firmness and reduce fine lines.

• Hydration Boost: Strengthens the skin barrier, enhancing moisture retention for smoother, plumper skin.

• Anti-Inflammatory Properties: Reduces puffiness and irritation while supporting the healing process.

 

How the Treatment Works

• Microinjections – The treatment is delivered through a series of small injections under the eyes, allowing the polynucleotides to penetrate deep into the skin.

• Skin Regeneration Begins – Over the following weeks, the treatment stimulates collagen production, repairs damaged tissue, and enhances hydration.

• Progressive Improvements – Fine lines, dark circles, and puffiness gradually reduce, revealing a firmer, smoother, and more youthful under-eye area.

Rejuran® Eye works in harmony with the skin’s natural healing process, providing long-lasting rejuvenation for brighter, healthier-looking eyes
For optimal, long-lasting results, a series of 3 treatments spaced 3-4 weeks apart is recommended.

What are the benefits?

• Skin Barrier Regeneration – Strengthens and thickens delicate under-eye skin

• Collagen Production – Stimulates skin repair for firmer, more youthful eyes

• Fine Lines & Wrinkles – Smooths crepey skin and reduces crow’s feet

• Dark Circles & Pigmentation – Brightens and evens out under-eye discoloration

• Sagging & Loss of Elasticity – Improves firmness and tightness in the under-eye area

• Hydration Boost – Deeply nourishes and prevents moisture loss

• Acne Scarring & Texture Concerns – Enhances skin regeneration for a smoother finish

• Minimised Pores & Oil Control– Refines skin texture and maintains balance

• Rejuran® Eye is the perfect solution for those looking to refresh, restore, and rejuvenate their under-eye area—achieving naturally youthful, radiant skin with long-lasting results.